Publications

Publications listed below are more current citations. For older publications, please visit this page.

  • Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SG
    Author Correction: Defining the consequences of genetic variation on a proteome-wide scale
    Nature . 2022 Jun;606(7915):E16. doi: 10.1038/s41586-022-04920-w. [ Pubmed ] [full text]
  • Crouse WL, Keele GR, Gastonguay MS, Churchill GA, Valdar W.A Bayesian model selection approach to mediation analysis
    PLoS Genet . 2022 May 9;18(5):e1010184. doi: 10.1371/journal.pgen.1010184. eCollection 2022 May [ Pubmed ] [full text]
  • Gerdes Gyuricza I, Chick JM, Keele GR, Deighan AG, Munger SC, Korstanje R, Gygi SP, Churchill GA.Genome-wide transcript and protein analysis highlights the role of protein homeostasis in the aging mouse heart
    Genome Res . 2022 May;32(5):838-852. doi: 10.1101/gr.275672.121. Epub 2022 Mar 11. [ Pubmed ] [full text]
  • Ouellette AR, Hadad N, Deighan A, Robinson L, O’Connell KO, Freund A, Churchill GA, Kaczorowski CCLife-long dietary restrictions have negligible or damaging effects on late-life cognitive performance: A key role for genetics in outcomes
    Neurobiol Aging . 2022 Jul 11;118:108-116. doi: 10.1016/j.neurobiolaging.2022.07.004. Online ahead of print. [ Pubmed ] [full text]
  • Perez BC, Bink MCAM, Svenson KL, Churchill GA, Calus MPL.Prediction performance of linear models and gradient boosting machine on complex phenotypes in outbred mice
    G3 (Bethesda) . 2022 Apr 4;12(4):jkac039. doi: 10.1093/g3journal/jkac039. [ Pubmed ] [full text]
  • Vincent M, Gerdes Gyuricza I, Keele GR, Gatti DM, Keller MP, Broman KW, Churchill GAQTLViewer: an interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations
    G3 (Bethesda) . 2022 Jul 29;12(8):jkac146. doi: 10.1093/g3journal/jkac146. [ Pubmed ] [full text]
  • Wright KM, Deighan AG, Di Francesco A, Freund A, Jojic V, Churchill GA, Raj AAge and diet shape the genetic architecture of body weight in diversity outbred mice
    Elife . 2022 Jul 15;11:e64329. doi: 10.7554/eLife.64329. [ Pubmed ] [full text]
  • Zhang G, Deighan A, Raj A, Robinson L, Donato HJ, Garland G, Leland M, Martin-McNulty B, Kolumam GA, Riegler J, Freund A, Wright KM, Churchill GA.Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice
    Genetics . 2022 Jan 4;220(1):iyab157. doi: 10.1093/genetics/iyab157.[ Pubmed ] [full text]
  • Dong C, Simonett SP, Shin S, Stapleton DS, Schueler KL, Churchill GA, Lu L, Liu X, Jin F, Li Y, Attie AD, Keller MP, Keleş S.
    INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants

    enome Biol . 2021 Aug 23;22(1):241. doi: 10.1186/s13059-021-02450-8. [ Pubmed ] [full text]

  • Gould RL, Craig SW, McClatchy S, Churchill GA, Pazdro R.

    Genetic mapping of renal glutathione suggests a novel regulatory locus on the murine X chromosome and overlap with hepatic glutathione regulation
    Free Radic Biol Med . 2021 Oct;174:28-39. doi: 10.1016/j.freeradbiomed.2021.07.035. Epub 2021 Jul 26. [ Pubmed ] [full text]

  • Gould RL, Craig SW, McClatchy S, Churchill GA, Pazdro R.

    Quantitative trait mapping in Diversity Outbred mice identifies novel genomic regions associated with the hepatic glutathione redox system
    Redox Biol . 2021 Oct;46:102093. doi: 10.1016/j.redox.2021.102093. Epub 2021 Aug 5. [ Pubmed ] [full text]

  • Keele GR, Zhang T, Pham DT, Vincent M, Bell TA, Hock P, Shaw GD, Paulo JA, Munger SC, Pardo-Manuel de Villena F, Ferris MT, Gygi SP, Churchill GA.

    Regulation of protein abundance in genetically diverse mouse populations
    Cell Genomics. 2021 August; 1(1). doi: 10.1101/2020.09.18.296657. [full text]

  • Keenan BT, Webster JC, Wiemken AS, Lavi-Romer N, Nguyen T, Svenson KL, Galante RJ, Churchill GA, Pickup S, Pack AI, Schwab RJ.

    Heritability of fat distributions in male mice from the founder strains of the Diversity Outbred mouse population
    G3 (Bethesda) . 2021 May 7;11(5):jkab079. doi: 10.1093/g3journal/jkab079. [ Pubmed ] [full text]

  • Keenan BT, Galante RJ, Lian K, Zhang L, Guo X, Veatch OJ, Chesler EJ, O’Brien WT, Svenson KL, Churchill GA, Pack AI

    The dihydropyrimidine dehydrogenase gene contributes to heritable differences in sleep in mice
    Curr Biol . 2021 Dec 6;31(23):5238-5248.e7. doi: 10.1016/j.cub.2021.09.049. Epub 2021 Oct 14. [ Pubmed ] [full text]

  • Korstanje R, Peters LL, Robinson LL, Krasinski SD, Churchill GA.

    The Jackson Laboratory Nathan Shock Center: impact of genetic diversity on aging
    Geroscience . 2021 Oct;43(5):2129-2137. doi: 10.1007/s11357-021-00421-2. Epub 2021 Jul 23. [ Pubmed ] [full text]

  • Palliyaguru DL, Shiroma EJ, Nam JK, Duregon E, Vieira Ligo Teixeira C, Price NL, Bernier M, Camandola S, Vaughan KL, Colman RJ, Deighan A, Korstanje R, Peters LL, Dickinson SL, Ejima K, Simonsick EM, Launer LJ, Chia CW, Egan J, Allison DB, Churchill GA, Anderson RM, Ferrucci L, Mattison JA, de Cabo R.

    Fasting blood glucose as a predictor of mortality: Lost in translation
    Cell Metab . 2021 Nov 2;33(11):2189-2200.e3. doi: 10.1016/j.cmet.2021.08.013. Epub 2021 Sep 10. [ Pubmed ] [full text]

  • Starcher AE, Peissig K, Stanton JB, Churchill GA, Cai D, Maxwell JT, Grider A, Love K, Chen SY, Coleman AE, Strauss E, Pazdro R

    A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatin
    G3 (Bethesda) . 2021 Oct 19;11(11):jkab293. doi: 10.1093/g3journal/jkab293. [ Pubmed ] [full text]

  • Takemon Y, Chick JM, Gerdes Gyuricza I, Skelly DA, Devuyst O, Gygi SP, Churchill GA, Korstanje R.

    Proteomic and transcriptomic profiling reveal different aspects of aging in the kidney
    Elife . 2021 Mar 9;10:e62585. doi: 10.7554/eLife.62585. [ Pubmed ] [full text]

  • Zhang G, Deighan A, Raj A, Robinson L, Donato HJ, Garland G, Leland M, Martin-McNulty B, Kolumam GA, Riegler J, Freund A, Wright KM, Churchill GA.

    Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice
    Genetics . 2021 Sep 25;220(1):iyab157. doi: 10.1093/genetics/iyab157. Online ahead of print. [ Pubmed ] [full text]

  • Zhang T, Keele GR, Churchill GA, Gygi SP, Paulo JA.

    Strain-Specific Peptide (SSP) Interference Reference Sample: A Genetically Encoded Quality Control for Isobaric Tagging Strategies
    Anal Chem . 2021 Mar 30;93(12):5241-5247. doi: 10.1021/acs.analchem.0c05483. Epub 2021 Mar 18. [ Pubmed ] [full text]

  • Choi K, Chen Y, Skelly DA, Churchill GA.
    Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics

    Genome Biol . 2020 Jul 27;21(1):183. doi: 10.1186/s13059-020-02103-2. [ Pubmed ] [full text]

  • Keenan BT, Galante RJ, Lian J, Simecek P, Gatti DM, Zhang L, Lim DC, Svenson KL, Churchill GA, Pack AI.

    High-throughput sleep phenotyping produces robust and heritable traits in Diversity Outbred mice and their founder strains.
    Sleep. 2020 May 12;43(5). doi: 10.1093/sleep/zsz278. PubMed PMID: 32074270; PubMed Central PMCID: PMC7215270. [ Pubmed ] [full text]

  • Linke V, Overmyer KA, Miller IJ, Brademan DR, Hutchins PD, Trujillo EA, Reddy TR, Russell JD, Cushing EM, Schueler KL, Stapleton DS, Rabaglia ME, Keller MP, Gatti DM, Keele GR, Pham D, Broman KW, Churchill GA, Attie AD, Coon JJ

    A large-scale genome-lipid association map guides lipid identification
    Nat Metab . 2020 Oct;2(10):1149-1162. doi: 10.1038/s42255-020-00278-3. Epub 2020 Sep 21. [ Pubmed ] [full text]

  • Ortmann D, Brown S, Czechanski A, Aydin S, Muraro D, Huang Y, Tomaz RA, Osnato A, Canu G, Wesley BT, Skelly DA, Stegle O, Choi T, Churchill GA, Baker CL, Rugg-Gunn PJ, Munger SC, Reinholdt LG, Vallier L.

    Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation
    Cell Stem Cell. 2020 Aug 11;. doi: 10.1016/j.stem.2020.07.019. [Epub ahead of print] [ Pubmed ] [full text]

  • Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, White CC, De Jager PL, Schneider JA, Bennett DA, Seyfried NT

    Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer’s Dementia
    ll Rep . 2020 Sep 1;32(9):108091. doi: 10.1016/j.celrep.2020.108091. [ Pubmed ] [full text]

  • Skelly DA, Czechanski A, Byers C, Aydin S, Spruce C, Olivier C, Choi K, Gatti DM, Raghupathy N, Keele GR, Stanton A, Vincent M, Dion S, Greenstein I, Pankratz M, Porter DK, Martin W, O’Connor C, Qin W, Harrill AH, Choi T, Churchill GA, Munger SC, Baker CL, Reinholdt LG.

    Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency
    Cell Stem Cell. 2020 Aug 7;. doi: 10.1016/j.stem.2020.07.005. [Epub ahead of print] [ Pubmed ] [full text]

  • Broman KW, Gatti DM, Svenson KL, Sen Ś, Churchill GA
    Cleaning Genotype Data from Diversity Outbred Mice

    G3 (Bethesda). 2019 May 7;9(5):1571-1579. doi: 10.1534/g3.119.400165. PubMed PMID: 30877082; PubMed Central PMCID: PMC6505173. [ Pubmed ] [full text]

  • Broman KW, Gatti DM, Svenson KL, Sen Ś, Churchill GA.

    Cleaning Genotype Data from Diversity Outbred Mice.
    G3 (Bethesda). 2019 Mar 15. pii: g3.400165.2019. doi: 10.1534/g3.119.400165. [Epub ahead of print] [ Pubmed ] [full text]
    [data]
    [software]

  • Broman KW, Gatti DM, Simecek P, Furlotte NA, Prins P, Sen Ś, Yandell BS, Churchill GA

    R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations
    Genetics. 2019 Feb;211(2):495-502. doi: 10.1534/genetics.118.301595. Epub 2018 Dec 27. [ Pubmed ] [full text]

  • Choi K, Raghupathy N, Churchill GA.

    A Bayesian mixture model for the analysis of allelic expression in single cells.
    Nat Commun. 2019 Nov 15;10(1):5188. doi: 10.1038/s41467-019-13099-0. PubMed PMID: 31729374; PubMed Central PMCID: PMC6858378. [ Pubmed ] [full text]

  • Choi K, Raghupathy N, Churchill GA.

    A Bayesian mixture model for the analysis of allelic expression in single cells.
    Nat Commun. 2019 Nov 15;10(1):5188. doi: 10.1038/s41467-019-13099-0. [ Pubmed ] [full text]

  • Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Vincent M, Mitok KA, Wang Z, Ishimura T, Simonett SP, Emfinger CH, Das R, Beck T, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD

    Gene loci associated with insulin secretion in islets from non-diabetic mice
    J Clin Invest. 2019 Jul 25;130. doi: 10.1172/JCI129143 [ Pubmed ] [full text]

  • Kemis JH, Linke V, Barrett KL, Boehm FJ, Traeger LL, Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Churchill GA, Amador-Noguez D, Russell JD, Yandell BS, Broman KW, Coon JJ, Attie AD, Rey FE.

    Genetic determinants of gut microbiota composition and bile acid profiles in mice.
    PLoS Genet. 2019 Aug;15(8):e1008073. doi: 10.1371/journal.pgen.1008073. eCollection 2019 Aug. PubMed PMID: 31465442; PubMed Central PMCID: PMC6715156. [ Pubmed ] [full text]

  • Kemis JH, Linke V, Barrett KL, Boehm FJ, Traeger LL, Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Churchill GA, Amador-Noguez D, Russell JD, Yandell BS, Broman KW, Coon JJ, Attie AD, Rey FE.

    Genetic determinants of gut microbiota composition and bile acid profiles in mice.
    PLoS Genet. 2019 Aug;15(8):e1008073. doi: 10.1371/journal.pgen.1008073. eCollection 2019 Aug. [ Pubmed ] [full text]

  • Mesner LD, Calabrese GM, Al-Barghouthi B, Gatti DM, Sundberg JP, Churchill GA, Godfrey DA, Ackert-Bicknell CL, Farber CR

    Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass.
    PLoS Genet. 2019 May;15(5):e1008123. doi: 10.1371/journal.pgen.1008123. eCollection 2019 May [ Pubmed ] [full text]

  • Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ.

    Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response.
    Pain. 2019 Mar 27. doi: 10.1097/j.pain.0000000000001571. [Epub ahead of print] [ Pubmed ] [full text]

  • Sarsani VK, Raghupathy N, Fiddes IT, Armstrong J, Thibaud-Nissen F, Zinder O, Bolisetty M, Howe K, Hinerfeld D, Ruan X, Rowe L, Barter M, Ananda G, Paten B, Weinstock GM, Churchill GA, Wiles MV, Schneider VA, Srivastava A, Reinholdt LG.

    The Genome of C57BL/6J “Eve”, the Mother of the Laboratory Mouse Genome Reference Strain.
    G3 (Bethesda). 2019 Jun 5;9(6):1795-1805. doi: 10.1534/g3.119.400071. PubMed PMID: 30996023 [ Pubmed ] [full text]

  • Zeiss CJ, Gatti DM, Toro-Salazar O, Davis C, Lutz CM, Spinale F, Stearns T, Furtado MB, Churchill GA.

    Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans.
    G3 (Bethesda). 2019 Aug 8;9(8):2637-2646. doi: 10.1534/g3.119.400232. PubMed PMID: 31263061; PubMed Central PMCID: PMC6686936. [ Pubmed ] [full text]

  • Attie AD, Churchill GA, Nadeau JH
    How mice are indispensable for understanding obesity and diabetes genetics.
    Curr Opin Endocrinol Diabetes Obes. 2017 Apr;24(2):83-91. doi: 10.1097/MED.0000000000000321 [ Pubmed ] [full text]
  • Gatti DM, Weber SN, Goodwin NC, Lammert F, Churchill GA
    Genetic Background Influences Susceptibility to Chemotherapy-Induced Hematotoxicity
    Pharmacogenomics J. 2017 Jun 13. doi: 10.1038/tpj.2017.23 [ Pubmed ] [full text]
    [data]
  • Morgan AP, Gatti DM, Najarian ML, Keane TM, Galante RJ, Pack AI, Mott R, Churchill GA, de Villena FP.
    Structural Variation Shapes the Landscape of Recombination in Mouse.
    Genetics. 2017 Jun;206(2):603-619. doi: 10.1534/genetics.116.197988 [ Pubmed ] [full text]
  • Percival CJ, Green R, Roseman CC, Gatti DM, Morgan JL, Murray SA, Donahue LR, Mayeux J, Pollard M, Pomp D, Marcucio R, Hallgrímsson B
    Developmental constraint through negative pleiotropy in the zygomatic arch [ Pubmed ] [full text]
    [data]
  • Simecek P, Forejt J, Williams RW, Shiroishi T, Takada T, Lu L, Johnson TE, Bennett B, Deschepper CF, Scott-Boyer MP, Pardo-Manuel de Villena F, Churchill GA.
    High-Resolution Maps of Mouse Reference Populations.
    G3 (Bethesda). 2017 Oct 5;7(10):3427-3434. doi: 10.1534/g3.117.300188. [ Pubmed ] [full text]
  • Srivastava A, Morgan AP, Najarian ML, Sarsani VK, Sigmon JS, Shorter JR, Kashfeen A, McMullan RC, Williams LH, Giusti-Rodríguez P, Ferris MT, Sullivan P, Hock P, Miller DR, Bell TA, McMillan L, Churchill GA, de Villena FP.
    Genomes of the Mouse Collaborative Cross
    Genetics. 2017 Jun;206(2):537-556. doi: 10.1534/genetics.116.198838. [ Pubmed ] [full text]
  • Tyler AL, Ji B, Gatti DM, Munger SC, Churchill GA, Svenson KL, Carter GW.
    Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice.
    Genetics. 2017 Jun;206(2):621-639. doi: 10.1534/genetics.116.198051. [ Pubmed ] [full text]
  • Winter JM, Gildea DE, Andreas JP, Gatti DM, Williams KA, Lee M, Hu Y, Zhang S; NISC Comparative Sequencing Program., Mullikin JC, Wolfsberg TG, McDonnell SK, Fogarty ZC, Larson MC, French AJ, Schaid DJ, Thibodeau SN, Churchill GA, Crawford NP.
    Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer.
    Cell Syst. 2017 Jan 25;4(1):31-45.e6. doi: 10.1016/j.cels.2016.10.018. Epub 2016 Dec 1 [ Pubmed ] [full text]

 

  • Attie AD, Churchill GA, Nadeau JH
    How mice are indispensable for understanding obesity and diabetes genetics.
    Curr Opin Endocrinol Diabetes Obes. 2017 Apr;24(2):83-91. doi: 10.1097/MED.0000000000000321 [ Pubmed ] [full text]
  • Gatti DM, Weber SN, Goodwin NC, Lammert F, Churchill GA
    Genetic Background Influences Susceptibility to Chemotherapy-Induced Hematotoxicity
    Pharmacogenomics J. 2017 Jun 13. doi: 10.1038/tpj.2017.23 [ Pubmed ] [full text]
    [data]
  • Morgan AP, Gatti DM, Najarian ML, Keane TM, Galante RJ, Pack AI, Mott R, Churchill GA, de Villena FP.
    Structural Variation Shapes the Landscape of Recombination in Mouse.
    Genetics. 2017 Jun;206(2):603-619. doi: 10.1534/genetics.116.197988 [ Pubmed ] [full text]
  • Percival CJ, Green R, Roseman CC, Gatti DM, Morgan JL, Murray SA, Donahue LR, Mayeux J, Pollard M, Pomp D, Marcucio R, Hallgrímsson B
    Developmental constraint through negative pleiotropy in the zygomatic arch [ Pubmed ] [full text]
    [data]
  • Simecek P, Forejt J, Williams RW, Shiroishi T, Takada T, Lu L, Johnson TE, Bennett B, Deschepper CF, Scott-Boyer MP, Pardo-Manuel de Villena F, Churchill GA.
    High-Resolution Maps of Mouse Reference Populations.
    G3 (Bethesda). 2017 Oct 5;7(10):3427-3434. doi: 10.1534/g3.117.300188. [ Pubmed ] [full text]
  • Srivastava A, Morgan AP, Najarian ML, Sarsani VK, Sigmon JS, Shorter JR, Kashfeen A, McMullan RC, Williams LH, Giusti-Rodríguez P, Ferris MT, Sullivan P, Hock P, Miller DR, Bell TA, McMillan L, Churchill GA, de Villena FP.
    Genomes of the Mouse Collaborative Cross
    Genetics. 2017 Jun;206(2):537-556. doi: 10.1534/genetics.116.198838. [ Pubmed ] [full text]
  • Tyler AL, Ji B, Gatti DM, Munger SC, Churchill GA, Svenson KL, Carter GW.
    Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice.
    Genetics. 2017 Jun;206(2):621-639. doi: 10.1534/genetics.116.198051. [ Pubmed ] [full text]
  • Winter JM, Gildea DE, Andreas JP, Gatti DM, Williams KA, Lee M, Hu Y, Zhang S; NISC Comparative Sequencing Program., Mullikin JC, Wolfsberg TG, McDonnell SK, Fogarty ZC, Larson MC, French AJ, Schaid DJ, Thibodeau SN, Churchill GA, Crawford NP.
    Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer.
    Cell Syst. 2017 Jan 25;4(1):31-45.e6. doi: 10.1016/j.cels.2016.10.018. Epub 2016 Dec 1 [ Pubmed ] [full text]

 

  • Chesler EJ, Gatti DM, Morgan AP, Strobel M, Trepanier L, Oberbeck D, McWeeney S, Hitzemann R, Ferris M, McMullan R, Clayshultle A, Bell TA, Pardo-Manuel de Villena F, Churchill GA
    Diversity Outbred Mice at 21: Maintaining allelic variation in the face of selection

    G3 (Bethesda). 2016 Dec 7;6(12):3893-3902. doi: 10.1534/g3.116.035527. [ Pubmed ] [full text]
    [ data ]

  • Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP

    Defining the consequences of genetic variation on a proteome-wide scale
    Nature. 2016 Jun 23;534(7608):500-5. doi: 10.1038/nature18270. Epub 2016 Jun 15 [ Pubmed ] [full text]
    [ data ]

  • Churchill GA

    Eric Lander and David Botstein on Mapping Quantitative Traits
    Genetics. 2016 May;203(1):1-3. doi: 10.1534/genetics.116.189803. Epub 2016 May 5 PMCID: PMC4858765 [full text]

  • Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Forster DW, French JE, Gabriel SI, Gatti DM, Garland T, Giagia-Athanasopoulou EB, Gimenez MD, Grize SA, Gunduz I, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, Lopez-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F

    R2d2 Drives Selfish Sweeps in the House Mouse
    Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15 PMCID: PMC4868115 [full text]

  • Gu T, Gatti DM, Srivastava A, Snyder EM, Raghupathy N, Simecek P, Svenson KL, Dotu I, Chuang JH, Keller MP, Attie AD, Braun RE, Churchill GA

    Genetic Architectures of Quantitative Variation in RNA Editing Pathways
    Genetics. 2016 Feb;202(2):787-98. doi: 10.1534/genetics.115.179481. Epub 2015 Nov 27 [ Pubmed ] [full text]

  • Jiang Z, Harrison DE, Parsons ME, McClatchy S, Jacobs L, Pazdro R

    Heritability of in vitro phenotypes exhibited by murine adipose-derived stromal cells
    Mamm Genome. 2016 Jul 8 [ Pubmed ] [full text]

  • Morgan AP, Fu CP, Kao CY, Welsh CE, Didion JP, Yadgary L, Hyacinth L, Ferris MT, Bell TA, Miller DR, Giusti-Rodriguez P, Nonneman RJ, Cook KD, Whitmire JK, Gralinski LE, Keller M, Attie AD, Churchill GA, Petkov P, Sullivan PF, Brennan JR, McMillan L, Pardo-Manuel de Villena F

    The Mouse Universal Genotyping Array: From Substrains to Subspecies
    G3 (Bethesda). 2015 Dec 18;6(2):263-79. doi: 10.1534/g3.115.022087 PMCID: PMC4751547 [full text]

  • Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MT, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, Sipila P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S

    Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness
    Nat Med. 2016 Jul;22(7):771-9. doi: 10.1038/nm.4115. Epub 2016 Jun 6 [ Pubmed ] [full text]

  • Nair KS, Cosma M, Raghupathy N, Sellarole MA, Tolman NG, de Vries W, Smith RS, John SW

    YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17
    Dis Model Mech. 2016 Aug 1;9(8):863-71. doi: 10.1242/dmm.024307. Epub 2016 Jun 9 PMCID: PMC5007977 [full text]

  • Tyler AL, Donahue LR, Churchill GA, Carter GW

    Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross
    PLoS Genet. 2016 Feb 1;12(2):e1005805. doi: 10.1371/journal.pgen.1005805. eCollection 2016 Feb PMCID: PMC4734753 [full text]

  • Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA,. Chesler EJ, Korstanje R, Peters LL
    Aging Research Using Mouse Models

    Curr Protoc Mouse Biol. 2015 Jun 1;5(2):95-133. doi: 10.1002/9780470942390.mo140195 PMCID: PMC4590775 [full text]

  • Baker CL, Kajita S, Walker M, Saxl RL, Raghupathy N, Choi K, Petkov PM and Paigen K

    PRDM9 drives evolutionary erosion of hotspots in Mus musculus through haplotype-specific initiation of meiotic recombination
    PLoS Genetics. 2015;11(1):e1004916 PMCID: PMC4287450 [ Full Text ]

  • Bogue MA, Churchill GA, Chesler EJ

    Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database
    Mamm Genome. 2015 Oct;26(9-10):511-20. doi: 10.1007/s00335-015-9595-6. Epub 2015 Aug 19 PMCID: PMC4602074 [full text]

  • Carmody RN, Gerber GK, Luevano JM, Gatti DM, Somes L, Svenson KL, Turnbaugh PJ

    Diet dominates host genotype in shaping the murine gut microbiota
    Cell Host Microbe. 2015 Jan 14;17(1):72-84. doi: 10.1016/j.chom.2014.11.010. Epub 2014 Dec 18 PMCID: PMC4297240 [full text]

  • Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH

    Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice
    Food Chem Toxicol 2015;76:19-26 PMCID: PMC4324012 [ Full Text ]

  • Dell’Acqua M, Gatti DM, Pea G, Cattonaro F, Coppens F, Magris G, Hlaing AL, Aung HH, Nelissen H, Baute J, Frascaroli E, Churchill GA, Inze D, Morgante M, Pe ME

    Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays
    Genome Biol. 2015 Sep 11;16:167. doi: 10.1186/s13059-015-0716-z PMCID: PMC4566846 [full text]

  • Didion JP, Morgan AP, Clayshulte AM, McMullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T. Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O’Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F

    A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2
    PLoS Genetics. 2015;11(2):e1004850 PMCID: PMC4334553 [ Full Text ]

  • French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard, KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA

    Diversity Outbred Mice Identify Population Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity
    Env. Health Persp., 2015;123(3):237-45 PMCID: PMC4348743 [ Full Text ]

  • Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, Valdar W, Heise MT, Pardo-Manuel de Villena F, Baric RS

    Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross
    PLoS Genet. 2015 Oct 9;11(10):e1005504. doi: 10.1371/journal.pgen.1005504. eCollection 2015 Oct PMCID: PMC4599853 [full text]

  • Niazi MK, Dhulekar N, Schmidt D, Major S, Cooper R, Abeijon C, Gatti DM, Kramnik I, Yener B, Gurcan M, Beamer G

    Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice
    Dis Model Mech. 2015 Sep;8(9):1141-53. doi: 10.1242/dmm.020867. Epub 2015 Jul 23 PMCID: PMC4582107 [full text]

  • Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ

    High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping
    G3 (Bethesda). 2015 Jul 28;5(10):2021-6. doi: 10.1534/g3.115.020784 PMCID: PMC4592984 [full text]

  • Rutledge H, Baran-Gale J, de Villena FP, Chesler EJ, Churchill GA, Sethupathy P, Kelada SN

    Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population
    BMC Genomics. 2015 Aug 25;16:633. doi: 10.1186/s12864-015-1732-9 PMCID: PMC4548451 [full text]

  • Simecek P, Churchill GA, Yang H, Rowe LB, Herberg L, Serreze DV, Leiter EH

    Genetic Analysis of Substrain Divergence in NOD Mice
    G3. 2015 PMCID: PMC4426365 [ Full Text ]

  • Walker M, Billings T, Baker CL, Powers N, Tian H, Saxl RL, Choi K, Hibbs MA, Carter GW, Handel MA, Paigen K, Petkov PM

    Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage
    Epigenetics Chromatin. 2015 Sep 7;8:31. doi: 10.1186/s13072-015-0024-6. eCollection 2015. PMCID: PMC4562113 [full text]

 

  • ogue MA, Peters LL, Paigen B, Korstanje R, Yuan R, Ackert-Bicknell C, Grubb SC, Churchill GA, Chesler EJ
    Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span

    J Gerontol A Biol Sci Med Sci. 2014 PMCID: PMC4707687 [ Full Text ]

  • Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW and Churchill GA

    Quantitative trait locus mapping methods for diversity outbred mice
    G3. 2014;4(9):1623-33 PMCID: PMC4169154 [ Full Text ]
    [ data]

  • Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA and Collins FS

    Integrative genetic analysis of allergic inflammation in the murine lung
    Am J Respir Cell Mol Biol. 2014 Sep;51(3):436-45. doi: 10.1165/rcmb.2013-0501OC PMCID: PMC4189492

  • Liu EY, Morgan AP, Chesler EJ, Wang W, Churchill GA, Pardo-Manuel de Villena F

    High-Resolution Sex-Specific Linkage Maps of the Mouse Reveal Polarized Distribution of Crossovers in Male Germline
    Genetics. 2014 Feb 27. doi: 10.1534/genetics.114.161653 PMCID: PMC4012503 [ Full Text ]

  • Munger SC, Raghupathy N, Choi K, Simons AK, Gatti DM, Hinerfeld DA, Svenson KL, Keller MP, Attie AD, Hibbs MA, Graber JH, Chesler EJ, and Churchill GA

    RNA-seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations
    Genetics. 2014;198(1):59-73 PMCID: PMC4174954 [ Full Text ]

  • Ram R, Mehta M, Balmer L, Gatti DM, Morahan G

    Rapid identification of major-effect genes using the collaborative cross
    Genetics. 2014 Sep;198(1):75-86. doi: 10.1534/genetics.114.163014 PMCID: PMC4174955 [full text]

  • Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ

    Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene
    Mamm Genome. 2014 Jun;25(5-6):211-22 PMCID: PMC4032469 [ Full Text ]

  • Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP and Kelada SN

    Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung
    Genetics. 2014;198(2):735-45 PMCID: PMC4196624 [ Full Text ]

  • Smallwood TL, Gatti DM, Quizon P, Weinstock GM, Jung KC, Zhao L, Hua K, Pomp D, Bennett BJ

    High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis
    G3 (Bethesda). 2014 Oct 23;4(12):2353-63. doi: 10.1534/g3.114.014704 PMCID: PMC4267931 [full text]

  • Yu W, Ackert-Bicknell C, Larigakis JD, MacIver B, Steers WD, Churchill GA, Hill WG, Zeidel, ML

    Spontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic trait
    Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1296-307 PMCID: PMC4042106
    [ Full Text ]

  • Yuan R, Gatti DM, Krier R, Malay E, Schultz D, Peters LL, Churchill GA, Harrison, DE, Paigen B

    Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1
    J Gerontol A Biol Sci Med Sci 2014 July 28 PMCID: PMC4481683 [ Full Text ]

  • Brockmann GA, Schäfer N, Hesse C, Heise S, Neuschl C, Wagener A, Churchill GA, Li
    Relationship between obesity phenotypes and genetic determinants in a mouse model for juvenile obesity

    Physiol Genomics. 2013 Sep 16;45(18):817-26. doi: 10.1152/physiolgenomics.00058.2013 PMID: 23922126 [ Full Text ]

  • Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT

    Modeling host genetic regulation of influenza pathogenesis in the collaborative cross
    PLoS Pathog. 2013 Feb;9(2):e1003196 PMCID: PMC3585141 [ Full Text ]

  • Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, Demeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST
    Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

    PLoS One. 2013;8(2):e56179. doi: 10.1371/journal.pone.0056179 PMCID: PMC3572953 [ Full Text ]

  • Kumar V, Kim K, Joseph C, Kourrich S, Yoo SH, Huang HC, Vitaterna MH, de Villena FP, Churchill GA, Bonci A, Takahashi JS

    C57BL/6N Mutation in Cytoplasmic FMRP interacting protein 2 Regulates Cocaine ResponseScience. 2013 Dec 20;342(6165):1508-12. doi: 10.1126/science.1245503. [ Pubmed ] [full text]

  • Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ

    High-precision genetic mapping of behavioral traits in the diversity outbred mouse population
    Genes Brain Behav. 2013 Feb 21. doi: 10.1111/gbb.12029 PMCID: PMC3709837 [ Full Text ]

  • McClatchy S, McGann D, Gotwals R, Baskett A, Churchill G

    Students as collaborators in systems biology research
    Science. 2013 May 31;340(6136):1061-2. doi: 10.1126/science.1229906 PMCID: PMC4088332 [ Full Text ]

 

  • Aljakna A, Choi S, Savage H, Hageman Blair R, Gu T, Svenson KL, Churchill GA, Hibbs M, Korstanje R
    Pla2g12b and Hpn Are Genes Identified by Mouse ENU Mutagenesis That Affect HDL Cholesterol

    PLoS One. 2012;7(8):e43139 PMCID: PMC3422231 [ Full Text ]

  • Andrus BM, Blizinsky K, Vedell PT, Dennis K, Shukla PK, Schaffer DJ, Radulovic J, Churchill GA, Redei EE

    Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models
    Mol Psychiatry. 2012 Jan;17(1):49-61 PMCID: PMC3117129 [ Full Text ]
    [ data ]

  • Kelada SNP, Aylor DL, Peck BCE, Ryan JF, Tavarez U, Buus RJ, Miller DR, Chesler EJ, Threadgill DW, Churchill GA, Pardo-Manuel de Villena F, Collins FS

    Genetic Analysis of Hematologic Parameters in Incipient Lines of the Collaborative Cross
    G3 (Bethesda). 2012 Feb;2(2):157-65 PMCID: PMC3284323 [ Full Text ]
    [ data ]

  • Leduc MS, Blair RH, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B

    Using bioinformatics and systems genetics to dissect HDL cholesterol levels in an MRL/MpJ x SM/J intercross
    J Lipid Res. 2012 Jun;53(6):1163-75 PMCID: PMC3351823 [ Full Text ]

  • Pajer K, Andrus BM, Gardner W, Lourie A, Strange B, Campo J, Bridge J, Blizinsky K, Dennis K, Vedell P, Churchill GA, Redei EE

    Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression
    Transl Psychiatry. 2012 Apr 17;2:e101. doi: 10.1038/tp.2012.26 PMCID: PMC3337072 [ Full Text ]

  • Phifer-Rixey M, Bonhomme F, Boursot P, Churchill GA, Piálek J, Tucker P, Nachman M

    Adaptive evolution and effective population size in wild house mice
    Mol Biol Evol. 2012 Oct;29(10):2949-55 PMCID: PMC3457769 [ Full Text ]
    [ data ]

  • Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA

    High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population
    Genetics. 2012 Feb;190(2):437-47 PMCID: PMC3276626 [ Full Text ]
    [ data ]

  • Thaisz J, Tsaih SW, Feng M, Philip V, Zhang Y, Yanas L, Sheehan S, Xu L, Miller DR, Paigen B, Chesler EJ, Churchill GA, Dipetrillo KJ

    Genetic analysis of albuminuria in Collaborative Cross and multiple mouse intercross populations
    Am J Physiol Renal Physiol. 2012 Oct;303(7):F972-81 PMCID: PMC3469684 [ Full Text ]

  • Zhang W, Korstanje R, Thaisz J, Staedtler F, Harttman N, Xu L, Feng M, Yanas L, Yang H, Valdar W, Churchill GA, DiPetrillo K

    Genome-Wide Association Mapping of Quantitative Traits in Outbred Mice
    G3 (Bethesda). 2012 Feb;2(2):167-74 PMCID: PMC3284324 [ Full Text ] [ data ]

  • Aitman TJ, Boone C, Churchill GA, Hengartner MO, Mackay TFC, Stemple DL
    The future of model organisms in human disease research
    Nat Rev Genet. 2011 Jul 18;12(8):575-82. doi: 10.1038/nrg3047

    PMID: 21765459  [ Full Text ]

  • Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, Pardo-Manuel de Villena F, Churchill GA

    Genetic analysis of complex traits in the emerging collaborative cross
    Genome Res. 2011 Aug;21(8):1223-38
    PMCID: PMC3149489 [ Full Text ]
    [ Highlight in Nature Reviews Genetics ] 
    [ data ]

  • Berndt A, Leme AS, Williams LK, Von Smith R, Savage HS, Stearns T, Tsaih SW, Shapiro SD, Peters LL, Paigen BJ, Svenson KL

    Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice
    Physiol Genomics. 2011 Jan 11; 43: 1-11
    PMCID: PMC3026348  [ Full Text ]
    [ data ]

  • Leduc MS, Hageman RS, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B

    Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice
    J Lipid Res. 2011 Sep;52(9):1672-82
    PMCID: PMC3151687 [ Full Text ]

  • Mathes WF, Aylor DL, Miller DR, Churchill GA, Chesler EJ, Pardo Manuel de Villena F, Threadgill DW, Pomp D

    Architecture of energy balance traits in emerging lines of the Collaborative Cross
    Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1124-34
    PMCID: PMC3118585 [ Full Text ]
    [ data ]

  • Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Shaw GS, Shinpock S, Manly KF, Miller DR, Donohue KD, Culiat CT, Churchill GA, Lariviere WR, Palmer AA, O’Hara BF, Voy BH, Chesler EJ

    Genetic analysis in the Collaborative Cross breeding population
    Genome Res. 2011 Aug;21(8):1223-38
    PMCID: PMC3149490 [ Full Text ]
    [ data ]

  • Threadgill DW, Pardo-Manuel de Villena F, Miller DR, Miller DR, Churchill GA

    The collaborative cross: a recombinant inbred mouse population for the systems genetic era
    ILAR J. 2011 Feb 8;52(1):24-31
    PMID: 21411855

  • Yang H, Wang JR, Didion JP, Buus RJ, Bell TA, Welsh CE, Bonhomme F, Yu AH, Nachman MW, Piálek J, Tucker P, Boursot P, McMillan L, Churchill GA, Pardo-Manuel de Villena F

    Subspecific origin and haplotype diversity in the laboratory mouse
    Nat Genet. 2011 May 29;43(7):648-55
    PMCID: PMC3125408 [ Full Text ]
    [ data ]

 

  • Hageman RS, Wagener A, Hantschel C, Svenson KL, Churchill GA, Brockmann GA

    High fat diet leads to tissue specific changes reflecting risk factors for diseases in DBA/2J mice
    Physiol Genomics. 2010 Jun;42(1):55-66
    PMCID: PMC2888560 [ Full Text ]
    [ data ]

  • Leduc MS, Hageman RS, Meng Q, Verdugo RA, Tsaih SW, Churchill GA, Paigen B, Yuan R

    Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains
    Aging Cell. 2010 Oct;9(5):823-36. doi: 10.1111/j.1474-9726.2010.00612.x
    PMCID: PMC3025299 [ Full Text ]
    [ data ]

  • Li Y, Tesson BM, Churchill GA, Jansen RC

    Critical reasoning on causal inference in genome-wide linkage and association studies
    Trends Genet. 2010 Dec;26(12):493-8. doi: 10.1016/j.tig.2010.09.002. Epub 2010 Oct 15
    PMCID: PMC2991400 [ Full Text ]

  • Peters LL, Shavit JA, Lambert AJ, Tsaih SW, Li Q, Su Z, Leduc MS, Paigen B, Churchill GA, Ginsburg D, Brugnara C

    Sequence variation at multiple loci influences red cell hemoglobin concentration
    Blood. 2010 Dec 16;116(25):e139-49
    PMCID: PMC3031420 [ Full Text ]

  • Tsaih SW, Pezzolesi MG, Yuan R, Warram JH, Krolewski AS, Korstanje R

    Genetic analysis of albuminuria in aging mice and concordance with loci for human diabetic nephropathy found in a genome-wide association scan
    Kidney Int. 2010 Feb;77(3):201-10
    PMCID: PMC2807478 [ Full Text ]
    [ data ]

 

Rocks and waves at Acadia National Park